Best Supplements for Improved Glycemia
Ranked by research evidence. Compare 31 supplements across 41 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Very low evidence3 studies
Across 3 animal studies, all reported beneficial effects of Lactobacillus rhamnosus-containing interventions on glycemia, with effect sizes ranging from moderate to large. The only statistically significant finding was in a study that combined Gastrodia elata extract with probiotics in high-fat diet-fed mice, showing improvements in hyperglycemia and insulin resistance. No human studies or dose data are available, limiting applicability.
- Very low evidence3 studies
Across 3 studies, 3 reported beneficial moderate-sized effects on glycemia. One randomized controlled trial in 80 adults with type 2 diabetes showed a statistically significant reduction in glycated hemoglobin and fasting plasma glucose. Evidence is limited due to minimal high-quality studies, unreported dose ranges, and short or unspecified study durations.
- Very lowLactobacillus rhamnosusAcross 3 animal studies, all reported beneficial effects of Lactobacillus rhamnosus-containing interventions on glycemia, with effect sizes ranging from moderate to large. The only statistically significant finding was in a study that combined Gastrodia elata extract with probiotics in high-fat diet-fed mice, showing improvements in hyperglycemia and insulin resistance. No human studies or dose data are available, limiting applicability.3 beneficial3 studies
- Very lowLactobacillus rhamnosus LRa05Across 3 studies, 3 reported beneficial moderate-sized effects on glycemia. One randomized controlled trial in 80 adults with type 2 diabetes showed a statistically significant reduction in glycated hemoglobin and fasting plasma glucose. Evidence is limited due to minimal high-quality studies, unreported dose ranges, and short or unspecified study durations.3 beneficial3 studies