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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus rhamnosus LRa05 and Improved Glycemia

Research synthesisVery low evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, 3 reported beneficial moderate-sized effects on glycemia, with 1 reaching statistical significance. The evidence primarily comes from a single RCT in 80 adults with type 2 diabetes and two supporting review/correction notes with limited original data. Doses, forms, and durations were not consistently reported.

  • Studied populations: adults with type 2 diabetes

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). One study is a correction notice with no original data; one is a review without direct primary results on this specific strain. Only 1 of 3 studies reports a statistically significant finding, and it tested a multi-strain probiotic, not LRa05 alone.

Generated May 12, 2026
3 of 3 papers
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