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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus rhamnosus and Improved Glycemia

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 animal studies, all reported beneficial effects of Lactobacillus rhamnosus or related Lactobacillaceae on glycemia, with effect sizes ranging from moderate to large. One study reported a statistically significant improvement. The evidence is limited to preclinical models (mice), and no human data are available. No consistent dose or duration data were reported.

  • Studied populations: Mice (db/db mice, high-fat diet-induced diabetes models, autochthonous lactobacilli from goat dairy products)

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. All studies are in animal models (mice), so relevance to humans is uncertain. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). No studies reported human dose, form, or duration data.

Generated Jun 11, 2026
3 of 3 papers
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