Lactobacillus crispatus LV5 and Restored Protective Effect in Colitis

• Beneficial effect of auto-aggregating Lactobacillus crispatus on experimentally induced colitis in mice.

  • 2005-02
  • Clinical Trial
  • FEMS Immunology & Medical Microbiology 43(2)
  • • I. Castagliuolo
    • F. Galeazzi
    • S. Ferrari
    • M. Elli
    • P. Brun
    • A. Cavaggioni
    • D. Tormen
    • G. Sturniolo
    • L. Morelli
    • G. Palù

  • PubMed: 15681150
  • DOI: 10.1016/J.FEMSIM.2004.08.011

  5 Insights on

  • Restored Protective Effect in Colitis

  • Low evidence
  • Highly Cited
  • Animal Study

  L. crispatus MU5 administered in a 30% sucrose solution, known to restore the aggregation phenotype, had a protective effect comparable to mice receiving L. crispatus M247.

  Effect

  Beneficial

  Effect size

  Large