Lactobacillus crispatus VPro 31 and Increased Production of Anti-inflammatory Cytokine IL-10

• Lactobacillus crispatus mediates anti-inflammatory cytokine interleukin-10 induction in response to Chlamydia trachomatis infection in vitro.

  • 2015-12
  • International Journal of Medical Microbiology 305(8)
  • • A. Rizzo
    • M. Fiorentino
    • E. Buommino
    • G. Donnarumma
    • A. Losacco
    • N. Bevilacqua

  • PubMed: 26372530
  • DOI: 10.1016/j.ijmm.2015.07.005

  7 Insights on

  • Increased Production of Anti-inflammatory Cytokine IL-10

  • Low evidence

  In contrast, a significant upregulation of the IL-10 expression in HeLa and J774 cells by L. crispatus and supernatant was also demonstrated.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes