Lactobacillus crispatus VPro 31 and Reduced Cytotoxicity

• Lactobacillus crispatus represses vaginolysin expression by BV associated Gardnerella vaginalis and reduces cell cytotoxicity.

  • 2018-04
  • Anaerobe 50
  • • J. Castro
    • A. Martins
    • M. E. Rodrigues
    • N. Cerca

  • PubMed: 29427630
  • DOI: 10.1016/j.anaerobe.2018.01.014

  2 Insights on

  • Reduced Cytotoxicity

  • Low evidence

  Using a chemically-defined medium simulating genital tract secretions, we have shown that pre-adhering Lactobacillus crispatus to Hela epithelial cells reduced cytotoxicity caused by Gardnerella vaginalis.

  Effect

  Beneficial

  Effect size

  Moderate