Lactobacillus fermentum CECT5716 and Improved Gut Microbiota Composition

• Long-term safety of early consumption of Lactobacillus fermentum CECT5716: A 3-year follow-up of a randomized controlled trial.

  • 2015-02-16
  • RCT
  • Pharmacological research 95
  • • J A Maldonado-Lobón
    • M Gil-Campos
    • J Maldonado
    • E López-Huertas
    • K Flores-Rojas
    • A D Valero
    • M V Rodríguez-Benítez
    • O Bañuelos
    • F Lara-Villoslada
    • J Fonollá
    • M Olivares

  • PubMed: 25697549
  • DOI: 10.1016/j.phrs.2015.01.006

  2 Insights on

  • Improved Gut Microbiota Composition

  • High evidence

  The pattern of faecal microbiota was also similar between both groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Lactobacillus fermentum CECT5716 ameliorates high fat diet-induced obesity in mice through modulation of gut microbiota dysbiosis.

  • 2021-05
  • Pharmacological research 167
  • • Jose Alberto Molina-Tijeras
    • Patricia Diez-Echave
    • Teresa Vezza
    • Laura Hidalgo-García
    • Antonio Jesús Ruiz-Malagón
    • Maria Jesús Rodríguez-Sojo
    • Miguel Romero
    • Iñaki Robles-Vera
    • Federico García
    • Julio Plaza-Diaz
    • Mónica Olivares
    • Juan Duarte
    • Maria Elena Rodríguez-Cabezas
    • Alba Rodríguez-Nogales
    • Julio Gálvez

  • PubMed: 33529749
  • DOI: 10.1016/j.phrs.2021.105471

  4 Insights on

  • Improved Gut Microbiota Composition

  • Low evidence
  • Animal Study

  gut dysbiosis. The probiotic restores Akkermansia sp. abundance and reduced Erysipelotrichi class and Clostridium spp presence as well as increased Bacteroides proportion.

  Effect

  Beneficial

  Effect size

  Moderate