Efficacy of Bifidobacterium breve CECT7263 for infantile colic treatment: an open-label, parallel, randomised, controlled trial.
- 2021-02-24
- RCT · n = 150
- Beneficial Microbes 12(1)
- J. Maldonado-Lobón
- R. Blanco-Rojo
- J. Maldonado
- M. A. Ali
- M. V. Almazán
- A. Suanes-Cabello
- E. Callejón
- R. Jaldo
- M. R. Benavides
- A. Negrillo
- A. Sañudo
- C. Rodríguez
- O. Bañuelos
- J. Fonollá
- M. Olivares
- PubMed: 33350361
- DOI: 10.3920/BM2020.0105
- High evidence
The percentage of reduction in the minutes of crying from baseline in the Bb group was significantly higher than that in the Simethicone group every week of the intervention (-40.3 vs -27.6% at 1-week; -59.2 vs -43.2% at 2-weeks; -64.5 vs -53.5% at 3-week and -68.5 vs -59.5% at 4-weeks, P<0.05).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 1×10^8 cfu/day