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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced Crying Time

Ranked by research evidence. Compare 9 supplements across 18 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • High evidence9 studies

    Across 9 studies, 8 reported beneficial effects of Lactobacillus reuteri DSM 17938 on reduced crying time, with effect sizes ranging from small to large; the predominant effect size was moderate. The most commonly studied doses were 1 × 10^8 to 5 × 10^8 colony-forming units (CFU) daily, and the primary population was infants with colic, particularly breastfed infants. Median study duration was 28 days, with effects typically observed within 3–4 weeks.

    Dose: 1 × 10^8 to 5 × 10^8 CFU daily
9 supplements
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