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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Peppermint

Safety profile

4 studies reporting safety data1 increased-risk finding

In one study, peppermint was associated with a 57% increased risk of any adverse event (RR 1.57, 95% CI 1.04-2.37). Other studies reported no significant differences in specific events such as vomiting, nausea, antiemetic use, and blood pressure. Three studies described peppermint as well tolerated with low rates of adverse events.

Caveats: Limited evidence base (4 studies); absence of serious adverse events does not establish safety. Studies were not primarily designed to assess safety, so rare events may not be detected.

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