Peppermint and Reduced Blood Pressure

Doses used in studies

μL/day: 100 (median 100, IQR 100–100) — 1 study

Time to effect

Median: 2.9 weeks · IQR 2.9 weeks–2.9 weeks · Range 2.9 weeks–2.9 weeks — Reported in 1 of 1 study

Safety in these studies

Overall tolerabilityReported
Loss to follow-up (N=1) and adverse events (N=1) were low, both occurring in the peppermint arm, and compliance was very high in the peppermint (93.3%) trial arm.
from: Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients w

1 of 1 paper

Effects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.

2026-04-23
RCT · n = 40
PloS one 21(4)
- Jonathan Sinclair
- Benjamin Sant
- XuanYi Du
- Gareth Shadwell
- Stephanie Dillon
- Bobbie Butters
- Lindsay Bottoms

PubMed: 42024666
DOI: 10.1371/journal.pone.0344538

7 Insights on

Reduced Blood Pressure

High evidence

adjusted systolic blood pressure at 20 days was significantly lower (b = -8.48 mmHg, 95% CI = -14.24 to -2.73, d = -0.94) in the peppermint trial arm (baseline = 130.05 mmHg, 20 days = 121.97 mmHg) than in placebo (baseline = 130.93 mmHg, 20 days = 131.05 mmHg).

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 100 μL per day