Lactobacillus fermentum ME-3 and Distinct Metabolic Profile

• Culture-based studies of intestinal lactobacilli in young people and centenarians.

  • 2026-03-10
  • Observational
  • Frontiers in microbiology 17
  • • Imbi Smidt
    • Tiiu Roop
    • Reet Mandar
    • Jelena Stsepetova
    • Siiri Koljalg
    • Kalle Kilk
    • Indrek Soidla
    • Mare Ainsaar
    • Helgi Kolk
    • Epp Sepp

  • PubMed: 41883793
  • DOI: 10.3389/fmicb.2026.1746411

  3 Insights on

  • Distinct Metabolic Profile

  • Low evidence

  Isolates from centenarians exhibited distinct carbohydrate fermentation patterns and metabolic profiles, including higher levels of acylcarnitines, arachidonic acid, and selected bile acids.

  • Neutral
  • Small effect