Lactobacillus fermentum VPro 14 and Improved Lipid Profile

• Oral administration of Lactobacillus fermentum CRL1446 improves biomarkers of metabolic syndrome in mice fed a high-fat diet supplemented with wheat bran.

  • 2021-03-23
  • Clinical Trial · n = 6
  • Food & Function 11(5)
  • • R. Medina
    • Matías Russo
    • Antonela Marquez
    • Héctor M. Herrera
    • M. C. Abeijón-Mukdsi
    • L. Saavedra
    • E. Hebert
    • Paola Gauffin-Cano

  • PubMed: 32421119
  • DOI: 10.1039/d0fo00730g

  26 Insights on

  • Improved Lipid Profile

  • Low evidence
  • Animal Study

  ...improvement of inflammatory profile, reduction of fatty infiltration in hepatocytes and modification of lipid profile (increased HDL-cholesterol and decreased LDL-cholesterol and triglyceride levels) were observed.

  Effect

  Beneficial

  Effect size

  Moderate

• Oral administration of Lactobacillus fermentum post-weaning improves the lipid profile and autonomic dysfunction in rat offspring exposed to maternal dyslipidemia.

  • 2021-04-26
  • RCT · n = 14
  • Food & Function 11(6)
  • • Y. de Oliveira
    • R. G. S. Cavalcante
    • M. P. Cavalcanti Neto
    • M. Magnani
    • V. Braga
    • E. L. de Souza
    • J. L. de Brito Alves

  • PubMed: 32524104
  • DOI: 10.1039/d0fo00514b

  5 Insights on

  • Improved Lipid Profile

  • Low evidence
  • Animal Study

  The intervention with the probiotic formulation of L. fermentum in male and female offspring reduced total cholesterol (TC) and increased HDL-c, but did not affect the insulin resistance induced by maternal dyslipidemia.

  Effect

  Beneficial

  Effect size

  Moderate