Lactobacillus gasseri and Improved Bone Regeneration

• Lactobacillus gasseri-derived postbiotics promote osteogenic differentiation in BMSCs via ameliorating mitochondrial oxidative stress.

  • 2026-01
  • Biochemical and biophysical research communications 795
  • • Ziwei Guo
    • Yun Yuan
    • Keyu Lu
    • Shi Yin
    • Wei Bi

  • PubMed: 41389616
  • DOI: 10.1016/j.bbrc.2025.153113

  3 Insights on

  • Improved Bone Regeneration

  • Low evidence
  • Animal Study

  Postbiotics (150 μg/mL) significantly enhanced BMSC proliferation, migration, and osteogenic differentiation... In vivo, postbiotic treatment significantly enhanced bone regeneration and reduced local inflammation in calvarial defects.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes