Lactobacillus helveticus VPro 13 and Reduced Inflammation Levels

• L-citrulline Enriched Fermented Milk with Lactobacillus helveticus Attenuates Dextran Sulfate Sodium (DSS) Induced Colitis in Mice.

  • 2022-01
  • RCT · n = 6
  • The Journal of Nutritional Biochemistry 99
  • • Sze Wing Ho
    • H. El‐Nezami
    • H. Corke
    • C. Ho
    • N. Shah

  • PubMed: 34587540
  • DOI: 10.1016/j.jnutbio.2021.108858

  12 Insights on

  • Reduced Inflammation Levels

  • Low evidence
  • Animal Study
  • Clinical

  All treatments reduced the body weight loss, disease activity index (DAI), histological scores, pro-inflammatory cytokine expression (IL-6, TNF-α and IFN-γ) and production (IL-4) (all P <0.05)...

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in d-galactosamine-treated rats

  • 2019-11-12
  • Clinical Trial
  • Applied Microbiology and Biotechnology 103(23-24)
  • • Qiangqiang Wang
    • L. Lv
    • Huiyong Jiang
    • Kaicen Wang
    • Ren Yan
    • Yating Li
    • Jianzhong Ye
    • Jingjing Wu
    • Qing Wang
    • Xiaoyuan Bian
    • Liya Yang
    • Xianwan Jiang
    • Jiaojiao Xie
    • Yanmeng Lu
    • Jian Shen
    • Lanjuan Li

  • PubMed: 31713675
  • DOI: 10.1007/s00253-019-10211-8

  20 Insights on

  • Reduced Inflammation Levels

  • Low evidence
  • Animal Study

  L. helveticus R0052 exhibited anti-inflammatory properties by downregulating Toll-like receptors, tumour necrosis factor-α and nuclear factor-κb transcription in liver samples and decreasing proinflammatory cytokine plasma concentrations.

  Effect

  Beneficial

  Effect size

  Moderate