Lactobacillus johnsonii LJ09 and Enhanced Brain-Derived Neurotrophic Factor Levels

• Lactobacillus johnsonii CJLJ103 Attenuates Scopolamine-Induced Memory Impairment in Mice by Increasing BDNF Expression and Inhibiting NF-κB Activation.

  • 2018-09-28
  • Clinical Trial
  • Journal of Microbiology and Biotechnology 28(9)
  • • Hae-Ji Lee
    • Su-Min Lim
    • Dong-Hyun Kim

  • PubMed: 30111074
  • DOI: 10.4014/jmb.1805.05025

  2 Insights on

  • Enhanced Brain-Derived Neurotrophic Factor Levels

  • Low evidence
  • Animal Study

  LJ treatment increased scopolamine-suppressed BDNF expression and CREB phosphorylation in the hippocampi of the brain.

  Effect

  Beneficial

  Effect size

  Moderate