Lactobacillus lactis LI-23 and Improved Intestinal Barrier Function

• Probiotic and antibacterial properties of recombinant Lactococcus lactis expressing the fusion antimicrobial peptides BMAP18-BSN37 in mice and chickens.

  • 2026-04
  • Poultry science 105(4)
  • • Ruibiao Wang
    • Yukai Lin
    • Yu Xia
    • Suxian Liu
    • Doudou Feng
    • Siyang Li
    • Tengyue Zhou
    • Huarun Sun
    • Jiyuan Shen
    • Bo Wen
    • Minghui Li
    • Chengshui Liao
    • Baoliang Qin
    • Jianhe Hu
    • Yuanfang Ma
    • Ke Ding
    • Lei Wang

  • PubMed: 41616534
  • DOI: 10.1016/j.psj.2026.106507

  4 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Animal Study

  NZ-BB enhanced body weight gain, supported immune organ development, and improved intestinal barrier integrity through upregulation of tight junction proteins (occludin, claudin-1, ZO-1) and anti-inflammatory cytokines (TGF-β, IL-4)

  Effect

  Beneficial

  Effect size

  Moderate