Lactobacillus paracasei Lpc-37 and Reduced Diarrhea Rate

• A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO).

  • 2017-08-23
  • RCT · n = 33
  • The Journal of antimicrobial chemotherapy 72(11)
  • • Anna K Barker
    • Megan Duster
    • Susan Valentine
    • Timothy Hess
    • Laurie Archbald-Pannone
    • Richard Guerrant
    • Nasia Safdar

  • PubMed: 28961980
  • DOI: 10.1093/jac/dkx254

  4 Insights on

  • Reduced Diarrhea Rate

  • High evidence
  • Clinical

  rate of diarrhoea (0.1 versus 0.3 days of diarrhoea/stool diary days submitted; P = 0.009)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  once-daily capsule