Lactobacillus paracasei SD5275 and Improved Gut Microbiome Diversity

• Probiotic supplementation during antibiotic treatment is unjustified in maintaining the gut microbiome diversity: a systematic review and meta-analysis.

  • 2023-07-19
  • Meta-Analysis
  • BMC medicine 21(1)
  • • Anna Júlia Éliás
    • Viktória Barna
    • Cristina Patoni
    • Dóra Demeter
    • Dániel Sándor Veres
    • Stefania Bunduc
    • Bálint Erőss
    • Péter Hegyi
    • László Földvári-Nagy
    • Katalin Lenti

  • PubMed: 37468916
  • DOI: 10.1186/s12916-023-02961-0

  1 Insight on

  • Improved Gut Microbiome Diversity

  • High evidence

  Quantitative data synthesis for Shannon (MD = 0.23, 95% CI: [(-)0.06-0.51]), Chao1 (MD = 11.59 [(-)18.42-41.60]) and observed OTUs ... diversity indices revealed no significant difference between probiotic supplemented and control groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No