Lactobacillus plantarum 14D and Improved Intestinal Barrier Function

• Probiotics improve intestinal ischemia-reperfusion injury: a systematic review and meta-analysis.

  • 2025-05-22
  • Systematic Review · n = 12
  • Frontiers in medicine 12
  • • Zicen Zhao
    • Yuxuan Wu
    • Yufang Leng
    • Liya Chang
    • Yu Wang
    • Dongbin Li
    • Yang Xing

  • PubMed: 40486191
  • DOI: 10.3389/fmed.2025.1546650

  4 Insights on

  • Improved Intestinal Barrier Function

  • High evidence

  a more intact intestinal barrier [occludin (2.83, 95% CI: 1.46 to 4.20 ...), ZO-1 (3.30, 95% CI: 1.58 to 5.01 ... ) and FITC-dextran (-3.83, 95% CI: -5.83 to -2.29 ...)]

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes