The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies.
- 2022-04-19
- Systematic Review · n = 2,817
- International journal of molecular sciences 23(9)
- Sauliha R Alli
- Ilona Gorbovskaya
- Jonathan C W Liu
- Nathan J Kolla
- Lisa Brown
- Daniel J Müller
- PubMed: 35562885
- DOI: 10.3390/ijms23094494
- High evidence
- Highly Cited
- Rigorous Journal
Probiotic and synbiotic, but not prebiotic, treatment showed a modest benefit in reducing depressive symptoms in patients with MDD over four to nine weeks.
- Effect
- Beneficial
- Effect size
- Small