Lactobacillus plantarum DSM 6596 and Reduced Pathogenic Bacterial Activity

• In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.

  • 2009-01
  • Antimicrobial agents and chemotherapy 53(1)
  • • Kaori Tanaka
    • Hiroshige Mikamo
    • Kenichi Nakao
    • Taku Ichiishi
    • Takatsugu Goto
    • Yuka Yamagishi
    • Kunitomo Watanabe

  • PubMed: 18955522
  • DOI: 10.1128/aac.00595-08

  1 Insight on

  • Reduced Pathogenic Bacterial Activity

  • Low evidence

  Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.

  Effect

  Beneficial

  Effect size

  Moderate