In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.
- 2009-01
- Antimicrobial agents and chemotherapy 53(1)
- Kaori Tanaka
- Hiroshige Mikamo
- Kenichi Nakao
- Taku Ichiishi
- Takatsugu Goto
- Yuka Yamagishi
- Kunitomo Watanabe
- PubMed: 18955522
- DOI: 10.1128/aac.00595-08
Study Design
- Population
- 63 reference species
- Methods
- The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems
The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.
Research Insights
Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.
- Effect
- Beneficial
- Effect size
- Moderate