In vitro activity of tomopenem (CS-023/RO4908463) against anaerobic bacteria.
- 2009-01
- Antimicrobial agents and chemotherapy 53(1)
- PubMed: 18955522
- DOI: 10.1128/aac.00595-08
Study Design
- Population
- 63 reference species
- Methods
- The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems
The antianaerobic activity of tomopenem, a new longer-half-life parenteral carbapenem, was compared with other carbapenems. Tomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem.
Research Insights
| Supplement | Dose | Health Outcome | Effect Type | Effect Size | Source |
|---|---|---|---|---|---|
| Lactobacillus plantarum DSM 6596 | — | Reduced Pathogenic Bacterial Activity | Beneficial | Moderate | View sourceTomopenem showed broad activity against 63 reference species. The activity of tomopenem against 293 clinical isolates was potent (MIC(90), 0.06 to 4 microg/ml) and comparable to those of meropenem and doripenem and more potent than that of panipenem. |