Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food “Tofu”
- 2017-01-27
- Clinical Trial
- PLOS ONE 12(1)
- Li Huang
- Cui-cui Duan
- Yujuan Zhao
- Lei Gao
- Chunhua Niu
- Jingbo Xu
- Shengyu Li
- PubMed: 28129335
- DOI: 10.1371/journal.pone.0170109
- Low evidence
- Highly Cited
- Rigorous Journal
- Animal Study
- Clinical
Compared to the mice that received AFB1 only, L. plantarum C88 treatment could weaken oxidative stress by enhancing the activity of antioxidant enzymes and elevating the expression of Glutathione S-transferase (GST) A3 through Nuclear factor erythroid (derived factor 2) related factor 2 (Nrf2) pathway.
- Effect
- Beneficial
- Effect size
- Moderate