Lactobacillus plantarum L-137 and Improved Glycemia

• Precision Microbiome Modulation: Exploring Lactobacillus spp. as A Targeted Strategy for Type 2 Diabetes Management.

  • 2026-03-04
  • Review
  • Current nutrition reports 15(1)
  • • Ann Sze Cheah
    • Ji Wei Tan
    • Faizul Jaafar
    • Wendy Wai Yeng Yeo

  • PubMed: 41779301
  • DOI: 10.1007/s13668-026-00739-3

  4 Insights on

  • Improved Glycemia

  • Low evidence

  Lactobacillus spp. supplementation alleviates insulin resistance in T2DM by modulating glucose metabolism and transport, exerting anti-inflammatory and anti-oxidative effects as well as restructuring gut microbiota.

  Effect

  Beneficial

  Effect size

  Moderate

• Heat-killed Lactobacillus plantarum L-137 attenuates obesity and associated metabolic abnormalities in C57BL/6 J mice on a high-fat diet

  • 2021-05-18
  • Clinical Trial
  • Bioscience of Microbiota, Food and Health 40(2)
  • • Rieko Yoshitake
    • Y. Hirose
    • S. Murosaki
    • G. Matsuzaki

  • PubMed: 33996364
  • DOI: 10.12938/bmfh.2020-040

  10 Insights on

  • Improved Glycemia

  • Low evidence
  • Rigorous Journal
  • Animal Study

  HK L-137 supplementation alleviated... elevation of plasma glucose

  Effect

  Beneficial

  Effect size

  Moderate