Lactobacillus plantarum Rosell-1012 and Reduced Pro-inflammatory Cytokine Levels

• Research protocol of the efficacy of probiotics for the treatment of alcohol use disorder among adult males: A comparison with placebo and acceptance and commitment therapy in a randomized controlled trial.

  • 2023-12-05
  • RCT
  • PloS one 18(12)
  • • Bingyu Zhang
    • Ruiling Zhang
    • Hongdu Deng
    • Ping Cui
    • Chunyan Li
    • Fan Yang
    • Mohammad Farris Iman Leong Bin Abdullah

  • PubMed: 38051740
  • DOI: 10.1371/journal.pone.0294768

  1 Insight on

  • Reduced Pro-inflammatory Cytokine Levels

  • High evidence

  Secondarily, this study compares the efficacy of probiotic and ACT in mitigating the severity of comorbid depression and anxiety symptoms; decreasing serum level of pro-inflammatory cytokines, such as interleukin 1β (IL-1β), interleukin 6 (IL-6), and tumor necrosis factor α (TNF-α).

  Effect

  Beneficial

  Effect size

  Small