Lactobacillus plantarum UALp-05M and Reduced Intestinal Inflammation

• The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet.

  • 2020
  • Clinical Trial
  • Food & Function 11(6)
  • • Yujun Liu
    • Yuan Gao
    • Fenglian Ma
    • Mengying Sun
    • Guangqing Mu
    • Y. Tuo

  • PubMed: 32530448
  • DOI: 10.1039/d0fo00439a

  7 Insights on

  • Reduced Intestinal Inflammation

  • Low evidence
  • Animal Study

  Oral administration of L. plantarum Y44 up-regulated the expression of colon tight junction protein such as claudin-1 and occludin, down-regulated p38 and phospho-p38 levels and reduced serum interleukin-8 (IL-8) and tumor necrosis factor-α (TNF-α).

  Effect

  Beneficial

  Effect size

  Large