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Lactobacillus plantarum UALp-05M

What does the research say about Lactobacillus plantarum UALp-05M?

2 health outcomes synthesised

Lactobacillus plantarum UALp-05M has been studied for 2 health outcomes, with the strongest evidence base focused on growth performance (4 animal studies) and reduced inflammation levels (3 in vitro/animal studies). All research to date is preclinical, using non-human models or cell lines — no human trials have been identified for this strain or closely related strains. No effective doses have been established in the available literature.

Strongest evidence No outcomes reached high or moderate evidence strength. The two syntheses both received a low evidence strength rating, indicating that all findings should be considered preliminary.

Mixed or weaker evidence

  • Improved Growth Performance: 4 of 4 animal studies (broiler chickens, weaning pigs, young piglets, fish) reported large beneficial effects, with 3 of 4 reaching statistical significance. However, all studies used different L. plantarum strains (B1, CJLP243, VSG3) rather than UALp-05M-specific, and applicability to humans is unclear.
  • Reduced Inflammation Levels: 3 of 3 studies (cell lines and mice) reported beneficial effects with predominantly large effect sizes, but only 1 of 3 reached statistical significance. All evidence is preclinical.

Effective dose patterns No dose information was reported in either synthesis — effective doses for growth performance or inflammation reduction could not be extracted from the available studies.

Population insights All evidence is derived from non-human populations: animal models (broiler chickens, weaning pigs, young piglets, fish) for growth performance, and cell lines/mice for inflammation. No data exist for any human population.

Notable caveats

  • The evidence base is small (4 and 3 studies, respectively) and conclusions should be considered preliminary.
  • Publication bias is a concern: null-result studies are less likely to be published or indexed.
  • No study used the specific strain L. plantarum UALp-05M — all used other L. plantarum strains.
  • No human trials have been identified; applicability of animal model results to human health is speculative.

Frequently asked

  • What is Lactobacillus plantarum UALp-05M good for according to research?
    Current research suggests Lactobacillus plantarum strains (though not specifically UALp-05M) may support improved growth performance in animals (4 studies, all showing beneficial effects) and reduced inflammation in cell and mouse models (3 studies, all showing beneficial effects). All evidence is preclinical and low strength.
  • What dose of Lactobacillus plantarum UALp-05M is typically used in studies?
    No effective dose or form information was reported in the available syntheses. Doses were not consistently reported across the included studies, and no human trials exist to guide dose recommendations.
  • Who benefits most from Lactobacillus plantarum UALp-05M?
    No human studies have been conducted. In animal research, beneficial effects on growth performance were observed in broiler chickens, weaning pigs, young piglets, and fish. Inflammation reduction was studied in cell lines and mice. Human benefit remains unknown.
  • Are there caveats or limitations in the research on Lactobacillus plantarum UALp-05M?
    Yes. The evidence base is very small (4 and 3 studies), all studies used different L. plantarum strains rather than UALp-05M specifically, and no human trials exist. Publication bias is a concern, as null results may be underreported. Applicability to humans is unclear.
  • Does Lactobacillus plantarum UALp-05M help improve growth performance?
    In 4 animal studies, L. plantarum strains showed large beneficial effects on growth performance (3 of 4 reached statistical significance). However, no human data exist, and the specific strain UALp-05M has not been tested. Evidence is considered low strength and preliminary.
  • Does Lactobacillus plantarum UALp-05M reduce inflammation?
    Three preclinical studies (cell lines and mice) reported beneficial effects of L. plantarum strains on reducing inflammation, with large effect sizes. Only one study reached statistical significance, and no human trials have been conducted. Evidence strength is low.

Most-studied combinations with Lactobacillus plantarum UALp-05M

most supplement research is combination research
Also studied with:Lactobacillus plantarum KABP-061 (9), Lactobacillus plantarum DR7 (8)
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