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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus plantarum UALp-05M and Reduced Inflammation Levels

Research synthesisVery low evidenceLarge effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects on reducing inflammation, with effect sizes ranging from moderate to large. One study, a cell-based experiment, found statistically significant inhibition of inflammatory cytokines (IL-6, IL-8, TNF-α) and increased IL-10. Doses were not reported, and study durations were not consistently available. The evidence base is too small (3 studies) to draw firm conclusions.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Studies were conducted in cell lines or animal models (mice, intestinal epithelial cells), not in humans — human relevance is uncertain. Doses and forms were not reported, preventing translation to supplementation guidance.

Generated May 12, 2026
3 of 3 papers
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