Lactobacillus reuteri MAK02L14R and Reduced Crying Duration

• The Efficacy and Safety of the Probiotic Bacterium Lactobacillus reuteri DSM 17938 for Infantile Colic: A Meta-Analysis of Randomized Controlled Trials

  • 2015-10-28
  • Meta-Analysis
  • PLOS ONE 10(10)
  • • Man Xu
    • Jiao Wang
    • Ning Wang
    • Fei Sun
    • Lin Wang
    • Xiao-hong Liu
    • Vincenzo Lionetti

  • PubMed: 26509502
  • DOI: 10.1371/journal.pone.0141445

  24 Insights on

  • Reduced Crying Duration

  • High evidence
  • Rigorous Journal

  Lactobacillus reuteri decreased crying time (min/d) at two weeks (weighted mean difference [WMD] = -42.89; 95% CI: -60.50 to -25.29; P = 0.000) and three weeks (WMD = -45.83; 95% CI: -59.45 to -32.21; P = 0.000).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes