Lactobacillus reuteri UALre-16 and Improved Intestinal Barrier Function

• Lactobacillus reuteri improves gut barrier function and affects diurnal variation of the gut microbiota in mice fed a high-fat diet.

  • 2020-01-15
  • Food & Function 10(8)
  • • Shuangqiu Li
    • Ce Qi
    • Hualing Zhu
    • R. Yu
    • C. Xie
    • Yuande Peng
    • S. Yin
    • Jianhui Fan
    • Suqing Zhao
    • Jin Sun

  • PubMed: 31304501
  • DOI: 10.1039/c9fo00417c

  17 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence

  Moreover, FN041 treatment improved intestinal epithelial barrier function

  Effect

  Beneficial

  Effect size

  Large

• Effects of Lactobacillus reuteri LR1 on the growth performance, intestinal morphology, and intestinal barrier function in weaned pigs.

  • 2018-04-12
  • RCT · n = 144
  • Journal of Animal Science 96(6)
  • • H. Yi
    • Li Wang
    • Yunxia Xiong
    • XiaoLu Wen
    • Zhilin Wang
    • Xuefen Yang
    • K. Gao
    • Zong-yong Jiang

  • PubMed: 29659876
  • DOI: 10.1093/jas/sky129

  6 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Rigorous Journal
  • Animal Study

  LR1 increased (P < 0.05) tight junction protein zonula occludens-1 and occludin transcripts in the mucosa of the jejunum and ileum, and those of mucin-2 in ileal mucosa.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes