Lactobacillus reuteri Ameliorates Intestinal Inflammation and Modulates Gut Microbiota and Metabolic Disorders in Dextran Sulfate Sodium-Induced Colitis in Mice
- 2020-07-31
- Clinical Trial
- Nutrients 12(8)
- Gang Wang
- Shuo Huang
- S. Cai
- Haitao Yu
- Yuming Wang
- Xiangfang Zeng
- S. Qiao
- PubMed: 32751784
- DOI: 10.3390/nu12082298
- Low evidence
- Animal Study
Overall, the results demonstrate that L. reuteri I5007 pretreatment could effectively alleviate intestinal inflammation by regulating immune responses and altering the composition of gut microbiota structure and function, as well as improving metabolic disorders in mice with colitis.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes