Evidence of Lactobacillus reuteri to reduce colic in breastfed babies: Systematic review and meta-analysis.
- 2021-12
- Meta-Analysis
- Complementary Therapies in Medicine 63
- Angela Pierina Dos Reis Buzzo Zermiani
- Ana Luiza Pelissari Peçanha de Paula Soares
- Bárbara Leticia da Silva Guedes de Moura
- Edson Roberto Arpini Miguel
- Luciana Dias Ghiraldi Lopes
- N. Santana
- T. Da Silva Santos
- I. G. Demarchi
- Jorge Juarez Teixeira
- PubMed: 34627993
- DOI: 10.1016/j.ctim.2021.102781
- High evidence
There was a significant response in reducing crying time (minutes/day) and treatment effectiveness (reduction ≥ 50% in average daily crying time) in the first week (p = 0.001 and p = 0.003, respectively). These results were similar in the second, third weeks (p < 0.001 for both outcomes) and fourth weeks (p<0.001 and p = 0.002, respectively).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes