Lactobacillus reuteri UALre-16 and Reduced Crying Time

• Lactobacillus reuteri DSM 17938 in Infantile Colic: A Randomized, Double-Blind, Placebo-Controlled Trial

  • 2010-09-01
  • RCT · n = 50
  • Pediatrics 126(3)
  • • F. Savino
    • Lisa Cordisco
    • V. Tarasco
    • E. Palumeri
    • R. Calabrese
    • R. Oggero
    • S. Roos
    • D. Matteuzzi

  • PubMed: 20713478
  • DOI: 10.1542/peds.2010-0433

  22 Insights on

  • Reduced Crying Time

  • High evidence
  • Highly Cited

  Responders (50% reduction in crying time from baseline) were significantly higher in the L reuteri group versus placebo group on days 7 (20 vs 8; P=.006), 14 (24 vs 13; P=.007), and 21 (24 vs 15; P=.036).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes