Lactobacillus reuteri and Reduced Depression Symptoms

• The efficacy and acceptability of Lactobacillus reuteri for the treatment of depression: A systematic review and meta-analysis.

  • 2025-07
  • Meta-Analysis · n = 1,258
  • General hospital psychiatry 95
  • • Qisheng Cheng
    • Yuxin Ran
    • Xiaolong Mo
    • Rui Xiao
    • Dian He
    • Siyi Guo
    • Haiyang Wang
    • Lanxiang Liu
    • Peng Xie

  • PubMed: 40339531
  • DOI: 10.1016/j.genhosppsych.2025.05.004

  2 Insights on

  • Reduced Depression Symptoms

  • High evidence
  • Clinical

  L. reuteri alone did not improve depressive symptoms.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No