Effect of oral administration involving a probiotic strain of Lactobacillus reuteri on pro-inflammatory cytokine response in patients with chronic periodontitis.
- 2014-02-09
- Clinical Trial · n = 24
- Archivum immunologiae et therapiae experimentalis 62(6)
- Anna K Szkaradkiewicz
- Janina Stopa
- Tomasz M Karpiński
- PubMed: 24509697
- DOI: 10.1007/s00005-014-0277-y
- Moderate evidence
- Clinical
After completion of the therapy with probiotic tablets, 18 (75%) of the patients of Group 1 have manifested a significant decrease in levels of studied pro-inflammatory cytokines (TNF-α, IL-1β and IL-17).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- Probiotic tablets (Prodentis) containing L. reuteri strain producing hydrogen peroxide – exact dose not specified