Lactobacillus rhamnosus GG and Increased Brain-derived Neurotrophic Factor Level

• Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response.

  • 2025-02-17
  • n = 56
  • Probiotics and antimicrobial proteins 17(6)
  • • Musab Işık
    • Fadime Köse
    • Cansu Özbayer
    • Özcan Budak
    • Rumeysa Keleş Kaya
    • Derya Güzel Erdoğan
    • Mehmet Arif Demirci
    • Songül Doğanay
    • Cahit Bağcı

  • PubMed: 39962033
  • DOI: 10.1007/s12602-025-10470-0

  5 Insights on

  • Increased Brain-derived Neurotrophic Factor Level

  • Low evidence
  • Rigorous Journal
  • Animal Study

  increased BDNF level, 5-HT1A, DRD1, ADRA-2A, GABA-A α1, CNR1 expression levels in the hippocampus

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes