Lactobacillus rhamnosus GG and Increased Cell Death

• Chemo-immunotherapeutic potential of Lactobacillus rhamnosus GG and its bioengineering for cancer therapy.

  • 2026-05
  • Biomaterials 328
  • • Zhaonan Liu
    • Qing Guan
    • Jianfeng Xin
    • Wei Tang
    • Yu Chen
    • Jiaying Zhang
    • Junjie Chen
    • Shijie Bi
    • Peng Wang
    • Jun Liu

  • PubMed: 41237436
  • DOI: 10.1016/j.biomaterials.2025.123848

  2 Insights on

  • Increased Cell Death

  • Low evidence

  Both LGG and its secretions exhibited potent cytotoxicity against various tumor cell lines, associated with mitochondrial dysfunction and apoptosis.

  Effect

  Beneficial

  Effect size

  Moderate