Lactobacillus rhamnosus GG and Increased IL-22-Producing CD4+ T Cell Count

• The Assessment of Multidimensional Clinical, Biological and Patient-Reported Outcomes to Evaluate the Efficacy of Add-On Lactobacillus rhamnosus GG Supplementation in Mild Ulcerative Colitis: A Randomized Pilot Trial.

  • 2026-04-23
  • RCT
  • Nutrients 18(9)
  • • Paola Maragno
    • Chiara Amoroso
    • Simone Conforti
    • Marco Michelon
    • Ivanna Honcharyuk
    • Clorinda Ciafardini
    • Daniele Noviello
    • Francesco Strati
    • Flavio Caprioli
    • Federica Facciotti
    • Maurizio Vecchi

  • PubMed: 42123931
  • DOI: 10.3390/nu18091329

  5 Insights on

  • Increased IL-22-Producing CD4+ T Cell Count

  • High evidence
  • Rigorous Journal
  • Clinical

  LGG+VitD3-supplemented patients showed ... increased frequencies of IL-22-producing CD4+ T cells.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  not specified in abstract