Lactobacillus rhamnosus GG and Reduced Antibiotic Use

• Lactobacillus rhamnosus GG Intake Modifies Preschool Children’s Intestinal Microbiota, Alleviates Penicillin-Associated Changes, and Reduces Antibiotic Use

  • 2016-04-25
  • RCT · n = 319
  • PLOS ONE 11(4)
  • • K. Korpela
    • A. Salonen
    • L. Virta
    • M. Kumpu
    • R. Kekkonen
    • W. D. de Vos

  • PubMed: 27111772
  • DOI: 10.1371/journal.pone.0154012

  2 Insights on

  • Reduced Antibiotic Use

  • High evidence
  • Large Human Trial
  • Rigorous Journal

  Finally, the treatment appeared to prevent certain bacterial infections for up to 3 years after the trial, as indicated by reduced antibiotic use.

  Effect

  Beneficial

  Effect size

  Moderate

  Dose

  not stated

• The Efficacy of Probiotics in Treating Upper Respiratory Tract Infections, Allergic Rhinitis, and Chronic Rhinosinusitis: A Systematic Review and Meta-Analysis.

  • 2026-04-28
  • Review
  • Microorganisms 14(5)
  • • Arezki Azzi
    • Assaf S Alotaibi
    • Muath S Alamri
    • Mohammed A Al-Dosari
    • Faris M Al Murdhi
    • Mohammed N Alatyani
    • Saad M Alnojaim
    • Mohammed A Alrufayyiq
    • Mohammed O Altowaijri

  • PubMed: 42197372
  • DOI: 10.3390/microorganisms14050986

  2 Insights on

  • Reduced Antibiotic Use

  • Low evidence
  • Clinical

  In URTIs, certain strains [e.g., Lactiplantibacillus plantarum DR7, Lactobacillus rhamnosus GG] reduced symptom duration and antibiotic use

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  not stated in abstract