Lactobacillus rhamnosus GG and Reduced Composite Outcome of Sepsis, Necrotizing Enterocolitis, or Mortality

• Lactobacillus rhamnosus GG to Reduce Necrotising Enterocolitis, Sepsis, and Mortality in Very Low Birth Weight Infants: A Randomized Controlled Trial.

  • 2026-01-14
  • RCT · n = 236
  • Indian pediatrics 63(7)
  • • Sachin Shah
    • Amita Kaul
    • Prerna Pandey
    • Surabhi Wattal
    • Rajesh Nare

  • PubMed: 41533318
  • DOI: 10.1007/s13312-025-00252-w

  6 Insights on

  • Reduced Composite Outcome of Sepsis, Necrotizing Enterocolitis, or Mortality

  • High evidence
  • Large Human Trial
  • Infants

  The primary composite outcome of sepsis, NEC or mortality was seen in 35 (30.4%) and 33 (27.2%) infants, respectively in the LGG and control groups (RR 0.85; 95%CI 0.48-1.50, P = 0.592).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No