Lactobacillus rhamnosus GG and Reduced Crying

Doses used in studies

CFU/day: 4.5 billion (median 4.5 billion, IQR 4.5 billion–4.5 billion) — 1 study

Time to effect

Median: 4 weeks · IQR 4 weeks–4 weeks · Range 4 weeks–4 weeks — Reported in 1 of 1 study

1 of 1 paper

Probiotic Lactobacillus rhamnosus GG therapy and microbiological programming in infantile colic: a randomized, controlled trial.

2015-07-07
RCT · n = 30
Pediatric research 78(4)
- Anna Pärtty
- Liisa Lehtonen
- Marko Kalliomäki
- Seppo Salminen
- Erika Isolauri

PubMed: 26151493
DOI: 10.1038/pr.2015.127

2 Insights on

Reduced Crying

High evidence
Infants

parents reported a decrease of 68% (95% confidence interval (CI): 58-78) in daily crying in the probiotic and 49% (95% CI: 32-66) in the placebo group (P = 0.05).

Effect: Beneficial
Effect size: Moderate
Significant: Yes
Dose: 4.5 × 10^9 cfu/day