Lactobacillus rhamnosus GG and Reduced Necrotizing Enterocolitis Stage II

• Lactobacillus rhamnosus GG as a probiotic for preterm infants: a strain specific systematic review and meta-analysis.

  • 2024-07-26
  • Meta-Analysis · n = 1,037
  • European journal of clinical nutrition 78(10)
  • • Anitha Ananthan
    • Haribalakrishna Balasubramanian
    • Chandra Rath
    • Saravanan Muthusamy
    • Shripada Rao
    • Sanjay Patole

  • PubMed: 39060543
  • DOI: 10.1038/s41430-024-01474-0

  5 Insights on

  • Reduced Necrotizing Enterocolitis Stage II

  • High evidence
  • Rigorous Journal
  • Clinical

  Meta-analysis of data from RCTs that used LGG as the sole probiotic showed significantly lower risk of NEC ≥Stage II [5 RCTs, n = 851, RR:0.50 (95% CI: 0.26, 0.93), P = 0.03] in the LGG group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes