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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus rhamnosus GG and Reduced Perceived Stress

Doses used in studies

CFU/day: 6 billion (median 6 billion, IQR 6 billion–6 billion) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 1 study

1 of 1 paper

The effect of probiotic supplementation on perceived stress and bowel function in healthy young adults: evidence from a randomized controlled trial in Makkah.
- 2026-01-06
- Clinical Trial
- Frontiers in nutrition 12
- - Essra A Noorwali
  - Abeer M Aljaadi
  - Wafaa F Abusudah
  - Fatmah A Bakhdar
  - Dania H Bin-Ali
  - Amani Alshinawi
  - Asma Bawazir
  - Raghad A Mutlaq
  - Heba A Maimany
  - Layan A Barnawi
  - Bshayer Murshed
  - Bayan Aljared
  - Firas S Azzeh
- PubMed: 41567324
- DOI: 10.3389/fnut.2025.1717047
4 Insights on
- Reduced Perceived Stress
- Moderate evidence
- Clinical
Post-intervention, stress score reductions were significantly greater in the probiotic group than controls (p=0.006).
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
6 × 10^9 CFU/day