Lactobacillus rhamnosus HN001 and Increased Granulocyte Count

• Postnatal Administration of Lactobacillus rhamnosus HN001 Ameliorates Perinatal Broad‐Spectrum Antibiotic‐Induced Reduction in Myelopoiesis and T Cell Activation in Mouse Pups

  • 2018-10-04
  • Clinical Trial
  • Molecular Nutrition & Food Research 62(22)
  • • E. Fuglsang
    • L. Krych
    • M. Lundsager
    • D. Nielsen
    • H. Frøkiaer

  • PubMed: 30211987
  • DOI: 10.1002/mnfr.201800510

  3 Insights on

  • Increased Granulocyte Count

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Oral administration of L. rhamnosus HN001 to neonatal pups (PND1-7) restores the antibiotic-induced changes of GMPs and granulocytes in BM and spleen, and further increases splenic granulocytes in control pups.

  Effect

  Beneficial

  Effect size

  Moderate