Daily Intake of Fermented Milk Containing Lactobacillus casei Shirota (Lcs) Modulates Systemic and Upper Airways Immune/Inflammatory Responses in Marathon Runners
- 2019-07-22
- RCT · n = 42
- Nutrients 11(7)
- M. Vaisberg
- V. Paixão
- E. Almeida
- Juliana M. B. Santos
- R. Foster
- Marcelo N. Rossi
- T. Pithon-Curi
- R. Gorjão
- C. M. Momesso
- M. Andrade
- J. R. Araújo
- M. C. Garcia
- M. Cohen
- E. C. Perez
- A. Santos-Dias
- R. Vieira
- A. Bachi
- PubMed: 31336570
- DOI: 10.3390/nu11071678
- High evidence
Higher proinflammatory cytokine levels in serum and nasal mucosa, and also lower salivary levels of SIgA and antimicrobial peptides, were found immediately post-marathon in the placebo group compared to other time points and to LcS group. In opposite, higher anti-inflammatory levels and reduced neutrophil infiltration on nasal mucosa were found in the LcS group compared to other time points and to the placebo group.
- Effect
- Beneficial
- Effect size
- Large