Lactobacillus rhamnosus LCS-742 and Increased Antioxidant Activity

• Exopolysaccharides produced by Lactobacillus rhamnosus GG alleviate hydrogen peroxide-induced intestinal oxidative damage and apoptosis through the Keap1/Nrf2 and Bax/Bcl-2 pathways in vitro.

  • 2022-01-27
  • Food & Function 12(20)
  • • Jinze Li
    • Qiuke Li
    • Nan Gao
    • Zhihua Wang
    • Feng Li
    • Jianping Li
    • A. Shan

  • PubMed: 34664577
  • DOI: 10.1039/d1fo00277e

  3 Insights on

  • Increased Antioxidant Activity

  • Low evidence

  EPSs exhibited promising antioxidative activities, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, hydroxyl radical (˙OH) and superoxide anion radical (O2˙-) scavenging, as well as ferrous ion chelating ability.

  Effect

  Beneficial

  Effect size

  Moderate