Lactobacillus rhamnosus Lr-32 and Improved Intestinal Barrier Function

• A Probiotic Mixture of Lactobacillus rhamnosus LR 32, Bifidobacterium lactis BL 04, and Bifidobacterium longum BB 536 Counteracts the Increase in Permeability Induced by the Mucosal Mediators of Irritable Bowel Syndrome by Acting on Zonula Occludens 1.

  • 2025-03-15
  • n = 28
  • International journal of molecular sciences 26(6)
  • • Maria Raffaella Barbaro
    • Francesca Bianco
    • Cesare Cremon
    • Giovanni Marasco
    • Vincenzo Stanghellini
    • Giovanni Barbara

  • PubMed: 40141298
  • DOI: 10.3390/ijms26062656

  1 Insight on

  • Improved Intestinal Barrier Function

  • Low evidence

  The co-incubation of Caco-2 cells with IBS supernatants and Serobioma (10^6 CFU/mL) avoided the paracellular permeability alterations that were induced by IBS supernatants alone (p < 0.001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes