Lactobacillus rhamnosus UALrh-18 and Increased Expression of Pro-apoptotic Proteins

• Lactobacillus rhamnosus induced epithelial cell apoptosis, ameliorates inflammation and prevents colon cancer development in an animal model.

  • 2016-10
  • RCT · n = 64
  • Biomedicine & Pharmacotherapy 83
  • • Yaser Gamallat
    • Abdo Meyiah
    • E. Kuugbee
    • A. Hago
    • Gift Chiwala
    • A. Awadasseid
    • Djibril Bamba
    • Xin Zhang
    • X. Shang
    • F. Luo
    • Y. Xin

  • PubMed: 27447122
  • DOI: 10.1016/j.biopha.2016.07.001

  9 Insights on

  • Increased Expression of Pro-apoptotic Proteins

  • Low evidence
  • Highly Cited
  • Rigorous Journal
  • Animal Study

  LGG treatment ... increased the expression of the pro-apoptotic proteins Bax, casp3 and p53 compared with DMH group.

  Effect

  Beneficial

  Effect size

  Moderate