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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus rhamnosus and Improved Immune Function

Research synthesisLow evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects of Lactobacillus rhamnosus on improved immune function, with effect sizes ranging from small to moderate. Two studies reached statistical significance. Evidence is drawn primarily from animal models (lambs, mice) and general reviews in healthy adults; no consistent dose or duration was reported across studies.

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Most studies were animal or in vitro models, and human data are limited to a single review mentioning healthy adults. No consistent dose, form, or duration data were extractable across studies.

Generated Jun 18, 2026
4 of 4 papers
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